Searchable abstracts of presentations at key conferences in endocrinology

ea0022p104 | Bone/Calcium | ECE2010

Wermer syndrome revealed by primary hyperparathyroidism: a case report

Nadia Mchirgui , Ali Insaf Hadj , Karima Khiari , Hela Cheikhrouhou , Youssef Lakhoua , Nejib Ben Abdallah

Multiple endocrine neoplasia type 1 (MEN1) is a rare but misleading disease. The diagnosis is evocated when two main lesions are present (parathyroid, pituitary gland, endocrine pancreas tumor: Gastrinoma). We studied a 36 year-old woman hospitalized in orthopedics for a neck femur fracture. A hypercalcaemia (Ca++=2.84 mmol/l) with elevated PTH=500 pg/ml were discovered before intervention. The bone biopsy concluded to primary hyperparathyroidism lesions.<p class="abstext"...

ea0022p490 | Female reproduction | ECE2010

Spontaneous pregnancy in Sheehan syndrome

Nadia Mchirgui , Insaf Hadj Ali , Karima Khiari , Youssef Lakhoua , Nejib Ben Abdallah

Spontaneous pregnancy in the course of Sheehan syndrome is extremely rare because of gonadotrophic insufficiency, which is almost present.The aim of our study is to analyse cases of pregnancies occurring spontaneously in patients with Sheehan syndrome.It is a retrospective study of 46 women who had a Sheehan syndrome diagnosed in the Internal Medicine and endocrinology department of Charles Nicolle Hospital during the period betwee...

ea0022p491 | Female reproduction | ECE2010

Sheehan syndrome: metabolic and hormonal abnormalities (46 cases)

Insaf Hadj Ali , Emna Haouat , Nadia Mchirgui , Karima Khiari , Youssef Lakhoua , Nejib Ben Abdallah

Sheehan syndrome is a global or partial pituitary defect occurring after an obstetrical haemorrhage.The aim of this study is to describe metabolic complications in 46 consecutive patients with Sheehan syndrome and to determine correlations between these complications and the clinical, hormonal and therapeutic aspects of this syndrome.All patients have had a physical examination: weight measurement, body mass index (BMI) determinati...

ea0022p629 | Neuroendocrinology and Pituitary (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Flexion contractures syndrome as the initial manifestation of hypopiptuitarism

Insaf Hadj Ali , Karima Khiari , Nadia Mchirgui , Youssef Lakhoua , Nejib Ben Abdallah

We present a 58 years old woman admitted in our department for bradycardia, diarrhea, epigastralgia, anorexia and weight loss. Physical examination showed low blood pressure and inability to walk or stand due to severe flexion contractures of the lower extremities without neurological abnormalities. The biological findings showed severe hyponatremia, hyerkaliemia tendency, low levels of plasma cortisol and ACTH suggesting pituitary adrenal axis deficiency. Hormonal investigati...

ea0056p206 | Calcium &amp; Vitamin D metabolism | ECE2018

Clinical, paraclinical, etiological and therapeutic particularities of severe hypercalcemia: A comparative study

Oueslati Ibtissem , Rached Amal , Mahfoudhi Madiha , Kaaroud Hayet , Khiari Karima , Turki Sami , Abdallah Nejib Ben , Abdallah Taieb Ben

Background: Severe hypercalcemia, defined as a serum calcium concentration ≥ 3.5 mmol/l or > 3 mmol/l associated with symptoms and signs of acute calcium intoxication, is a rare but a potentially life threatening condition. The aim of this study was to assess clinical, paraclinical, etiological and therapeutic features of severe hypercalcemia and to determine its outcome.Methods: It was a retrospective, descriptive and comparative study conduct...